MicroRNA-497 Suppresses Proliferation and Induces Apoptosis in Prostate Cancer Cells
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چکیده
منابع مشابه
MicroRNA-497 induces apoptosis through downregulating XIAP in hepatic cancer
Hepatic cancer is one of the important malignant tumors in digestive system. MicroRNAs regulate cell growth and other cell behaviors through signaling pathway. This study investigated the role of microRNA-497 on LM3 cell viability, proliferation, and apoptosis. MicroRNA-497 and scramble microRNA (miRNA) were synthetized and transfected to hepatic cancer cell line LM3 using lipofectamine. LM3 ce...
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MicroRNA-497 (miR-497) has been reported to be downregulated in certain types of cancer, including breast, gastric, endometrial, colorectal and prostate cancer as well as hepatocellular and nasopharyngeal carcinoma. The present study aimed to investigate the underlying mechanism of the tumor suppressor function of miR‑497 in prostate cancer. Following transfection with miR‑497, the DU145 and PC...
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ژورنال
عنوان ژورنال: Asian Pacific Journal of Cancer Prevention
سال: 2013
ISSN: 1513-7368
DOI: 10.7314/apjcp.2013.14.6.3499